Dosing Information
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Nexavar — Convenient Oral Dosing: 400 mg Twice Daily

Recommended daily dose for Nexavar

Nexavar dosing does not need to be adjusted on the basis of

  • Age (above 65 years)

  • Mild to moderate hepatic impairment

    – No data is available on patients with Child-Pugh class C (severe) impairment

  • Mild to moderate renal impairment

    – No data is available on patients requiring dialysis

Nexavar — management and duration of therapy

Important dosing considerations

Management of suspected adverse drug reactions may require temporary interruption or dose reduction of Nexavar.

When dose reduction is necessary, the Nexavar dose should be reduced to two tablets of 200 mg once daily.

Duration of therapy

Treatment should continue as long as clinical benefit is observed or until unacceptable toxicity occurs.


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